[Biotechnology] A yellow liquid that temporarily turns skin transparent when applied penetrates the skin of a living mouse， successfully allowing researchers to observe the internal organs and brain．
Researchers from Stanford University and other institutions have published a research report proposing a method to non-invasively observe the inside of living organisms, such as organs, by making the tissues above them transparent to visible light. A paper published by researchers from Stanford University and other institutions in the US, entitled “Achieving optical transparency in live animals with absorbing molecules,” is a research report proposing a method for non-invasively observing the inside of living organisms, such as organs, by making the tissues above them transparent to visible light. Using this method, the skin of a living animal can be temporarily made transparent, allowing internal tissue to be observed. When trying to see inside a living organism’s body using light, there is a problem that the light is scattered and it is not possible to see deep inside. To solve this problem, the research team used a yellow food coloring called tartrazine. It is widely used in the food industry and contains molecules that absorb most light, including blue and ultraviolet light. When an aqueous solution of this dye is applied to the skin, the refractive index of the solution changes, so that it matches the refractive index of tissue components, particularly lipids. As a result, light scattering within the skin tissue is reduced and light transmission is improved, as with defogginess. This mechanism makes it possible to achieve optical transparency of biological tissue. By applying a dye solution to the abdomen and head of the mice, the research team was able to observe internal organs and cerebral blood vessels. Specifically, the liver, intestines, and bladder were visible through the abdominal skin. For example, it made it possible to observe intestinal peristalsis (muscular contractions that move food) and by applying dye to the skin of the head, the blood vessels in the brain were visible. The effect is temporary; once the pigment is washed off, the treated skin reverts to its normal color and the effect is lost. *For the full article, please see the source below: September 11, 2024, it media news.
This is good news for diseases where you can’t see the details without open surgery. I was told it might be a malignant tumor, so I had surgery 15 years ago, but it turned out to be benign. As a result, I was left with a huge stitch that was over 20cm long.
>>25 I had surgery on my cheek when I was in kindergarten and I still have scars from the incisions, but in elementary school I was always being praised for being a pirate and it was fun.
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